Theo D. Palmer

This paper develops a hydrogel system to guide single-lumen neuroepithelial tissue formation from iPSCs, identifying matrix stress relaxation and tensional homeostasis as key regulators.

The paper identifies molecular pathways associated with neurodevelopmental disorder subgroups using neuroimaging data from mice and humans.

The paper identifies a microRNA cluster unique to placental mammals that promotes corticospinal neuron identity by repressing LMO4, a callosal gene, thereby contributing to neuronal subtype diversity in the mammalian brain.

The paper generates 65 hiPSC clones with 16p11.2 CNVs and identifies transcriptional changes in neural development using RNA-Seq.

The paper investigates the molecular effects of 16p11.2 CNVs on gene expression and DNA methylation using an iPSC-to-iN model and identifies potential contributing genes.