Mammalian epigenomic conservation of promoters and enhancers in the heart associates with trait-associated variation and impacts cardiomyocyte phenotypes
Stephanie Frost, Diego M. Fernández‐Aroca, Elise Parey, Adrian Rodriguez-Gonzalez, Daniel Pavon-Heredia, Diego Villar
The paper identifies epigenomically conserved promoters and enhancers in the heart, links them to cardiovascular trait variation, and shows their impact on cardiomyocyte phenotypes through experimental validation.
Heart · Jun 1, 2026Peer-reviewedGenomics