Diego M. Fernández‐Aroca

This study shows that AXL inhibitors dubermatinib and bemcentinib have antitumour effects in soft tissue sarcoma that are largely independent of AXL inhibition.

The paper identifies epigenomically conserved promoters and enhancers in the heart, links them to cardiovascular trait variation, and shows their impact on cardiomyocyte phenotypes through experimental validation.

This study investigates epigenomic changes in left and right atria of atrial fibrillation patients compared to controls, identifying dysregulated loci and epigenetic mechanisms.

This paper shows dinaciclib increases radiosensitivity in some cancer cell lines by inhibiting CDK12, reducing BRCA1, and promoting p53-dependent senescence.

The paper uses phylogenetic modeling to analyze epigenomic changes in mole-rats and identifies regulatory elements associated with metabolic and hypoxia-related traits.