Improved de novo Genome Assembly: Linked-Read Sequencing Combined with Optical Mapping Produce a High Quality Mammalian Genome at Relatively Low Cost
DW Mohr, Ahmed Naguib, NI Weisenfeld, V Kumar, Preyas Shah, DM Church, David B. Jaffe, AF Scott
This paper combines linked-read sequencing and optical mapping to improve de novo genome assembly for the Hawaiian Monk seal, achieving higher scaffold quality and length than existing methods.
bioRxiv · Apr 19, 2017 · PreprintGenomics