Author

Preyas Shah

10X Genomics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:genome assembly· 4 Assay:whole-genome sequencing· 4 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David B. JaffeiD· 2 shared Deanna M. ChurchiD· 2 shared Francesca Meschi· 2 shared Shamoni MaheshwariiD· 2 shared Stephen R. WilliamsiD· 2 shared Vijay Kumar· 2 shared Adam J. LoweiD· 1 shared Adrian N. Fehr· 1 shared

Activity by Year

2016-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

David B. JaffeORCID

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5 papers

Recent·Most cited

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Ansuman T. Satpathy, Jeffrey M. Granja, Kathryn E. Yost, Yanyan Qi, Francesca Meschi, Geoffrey P. McDermott, Brett N. Olsen, Maxwell R. Mumbach, Sarah E. Pierce, M. Ryan Corces, Preyas Shah, Jason C. Bell, Darisha Jhutty, Corey M. Nemec, Jean Wang, , Howard Y. Chang

The paper uses scATAC-seq to analyze chromatin accessibility in immune cell development and tumor microenvironments, identifying regulatory elements and trajectories associated with cell differentiation and therapy response.

Nature Biotechnology · Aug 1, 2019Peer-reviewedGenomics

Resolving the Full Spectrum of Human Genome Variation using Linked-Reads

Patrick Marks, Sarah Garcia, Álvaro Martínez Barrio, Kamila Belhocine, Jorge Bernate, Rajiv Bharadwaj, Keith P. Bjornson, Claudia Catalanotti, Josh Delaney, Adrian N. Fehr, Ian T. Fiddes, Brendan D. Galvin, Haynes Heaton, Jill Herschleb, Christopher M. Hindson, , Deanna M. Church

This paper introduces Linked-Reads as a method to comprehensively analyze genome variation, showing it can detect both small and large variants and reconstruct haplotypes more effectively than short-read sequencing.

Genome Research · Apr 1, 2019Peer-reviewedGenomics

Reference Quality Assembly of the 3.5 Gb genome of Capsicum annuum from a Single Linked-Read Library

Amanda M. Hulse‐Kemp, Shamoni Maheshwari, Kevin M. Stoffel, Theresa A. Hill, David B. Jaffe, Stephen R. Williams, Neil Weisenfeld, Srividya Ramakrishnan, Vijay Kumar, Preyas Shah, Michael C. Schatz, Deanna M. Church, Allen Van Deynze

This study uses Linked-Read sequencing to assemble a high-quality, contiguous reference genome for Capsicum annuum, demonstrating its utility for complex plant genomes.

Horticulture Research · Jan 12, 2018Peer-reviewedGenomics

Improved de novo Genome Assembly: Linked-Read Sequencing Combined with Optical Mapping Produce a High Quality Mammalian Genome at Relatively Low Cost

DW Mohr, Ahmed Naguib, NI Weisenfeld, V Kumar, Preyas Shah, DM Church, David B. Jaffe, AF Scott

This paper combines linked-read sequencing and optical mapping to improve de novo genome assembly for the Hawaiian Monk seal, achieving higher scaffold quality and length than existing methods.

bioRxiv · Apr 19, 2017 · PreprintGenomics

Direct determination of diploid genome sequences

Neil I Weisenfeld, Vijay Kumar, Preyas Shah, Deanna Church, David B Jaffe

This paper introduces a low-cost method to generate true diploid de novo genome assemblies using 10x Genomics and a new algorithm, Supernova, achieving contigs, phase blocks, and scaffolds longer than 100 kb, 2.5 Mb, and 15 Mb respectively.

bioRxiv · Aug 19, 2016Genomics