Structural and biophysical insights into the unique RNase YicC
Ruoxi Wu, Harsha Venkatesh, Carisse Lansiquot, Sarah A. Barnes, Afrooz Golestanian, Olga Rechkoblit, Alisha N. Jones, David H. Bechhofer, Michael B. Lazarus
This study reveals the structural and biophysical mechanisms of YicC, a novel bacterial RNase, showing its RNA binding and cleavage mechanism involving Mg2+ ions and dimeric conformations.
bioRxiv · Sep 17, 2026 · PreprintBiochemistry