Tendon response to matrix unloading is determined by the patho-physiological niche
Stefania L. Wunderli, Ulrich Blache, Agnese Beretta-Piccoli, Barbara P. Niederöst, Claude N. Holenstein, Fabian S. Passini, Unai Silván, Louise Bundgaard, Ulrich auf dem Keller, Jess Gerrit Snedeker
This study shows that tendon tissue response to mechanical unloading depends on the simulated physiological niche, with oxidative stress driving proteolytic matrix breakdown.
Matrix Biology · Jan 7, 2020Peer-reviewedMolecular Biology