Single-Cell Roadmap of Early Hemato-Endothelial Development: Functions of Atf3, Zfp711 and Bcl6b
Rıdvan Çeti̇n, Giulia Picco, Jente van Staalduinen, Eric M. Bindels, Remco Michiel Hoogenboezem, Gregory van Beek, Mathijs Arnoud Sanders, Yaren Fidan, Ahmet Korkmaz, Joost H. Gribnau, Jeffrey van Haren, Danny Huylebroeck, Eskeatnaf Mulugeta, Frank G. Grosveld
The paper investigates the roles of Atf3, Zfp711, and Bcl6b in early hemato-endothelial lineage specification using scRNA-seq and KO mESCs, finding distinct effects on mesodermal and hematopoietic lineages.
Development · Nov 7, 2025Peer-reviewedDevelopmental Biology