Gregory van Beek

scRIPT is a single-cell lineage-tracing method that improves coverage and reliability in differentiation protocols by integrating rapid barcoding, sorting, and sequencing with quality control.

This study identifies KIT+ ILC2s as an epigenomically plastic state linked to immune disease susceptibility and shows that STAT5 activation by cytokines induces this phenotype.

The paper investigates the roles of Atf3, Zfp711, and Bcl6b in early hemato-endothelial lineage specification using scRNA-seq and KO mESCs, finding distinct effects on mesodermal and hematopoietic lineages.

This paper shows that chemotherapy causes long-term bone marrow dysfunction by impairing hematopoietic stem cells, which can be reversed by mitochondrial-targeted treatment.