Identification of novel candidate regulators of human naive pluripotency by means of a genetic switch utilizing the chimeric receptor G-CSFR:GP130
Tahereh Kiani, Claire Santamaria, Nathalie Doerflinger, Aikaterini Kafousi, Cloé Rognard, Ambre Bender, Michaël Dumas, Michaël Weber, Alexandre Bruneau, Laurent David, Pierre Savatier, Pierre-Yves Bourillot
This study identifies novel regulators of human naive pluripotency using a genetic switch that activates STAT3 and JAK signaling, revealing key genes and mechanisms involved in reprogramming.
bioRxiv · Apr 9, 2025 · PreprintCell Biology