Author

Pierre-Yves Bourillot

Lyon 1 UniversitéORCID 0000-0003-1657-8555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:long-read sequencing· 1 Organism:mouse· 1

Frequent Co-Authors

Nathalie DoerflingeriD· 2 shared Pierre SavatieriD· 2 shared Aikaterini Kafousi· 1 shared Alexandre BruneauiD· 1 shared Ambre BenderiD· 1 shared Claire ChazaudiD· 1 shared Claire Santamaria· 1 shared Cloé RognardiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

Nathalie DoerflingerORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 23, 2025

A STAT3-regulated lncRNA integrates microRNA biogenesis and sequestration to safeguard naive pluripotency

Vincent Giudice, Florence Perold, Yannicke Pijoff…·Pierre-Yves Bourillot

The paper identifies Asgard, a STAT3-regulated lncRNA, which controls microRNA biogenesis and sequestration to maintain naive pluripotency in mouse embryonic stem cells.

DOI 10.1101/2025.09.23.677977

mouselong-read sequencing

𝕏 PostBluesky

Cell BiologybioRxivPreprintApr 9, 2025

Identification of novel candidate regulators of human naive pluripotency by means of a genetic switch utilizing the chimeric receptor G-CSFR:GP130

Tahereh Kiani, Claire Santamaria, Nathalie Doerflinger…·Pierre-Yves Bourillot

This study identifies novel regulators of human naive pluripotency using a genetic switch that activates STAT3 and JAK signaling, revealing key genes and mechanisms involved in reprogramming.

DOI 10.1101/2025.04.09.647577

humanbulk RNA-seq

𝕏 PostBluesky