Nathalie Doerflinger

This study shows Netrin-1 supports naive pluripotency in hESCs by modulating epigenetic and signaling pathways, with effects dependent on culture conditions.

The paper identifies Asgard, a STAT3-regulated lncRNA, which controls microRNA biogenesis and sequestration to maintain naive pluripotency in mouse embryonic stem cells.

This study identifies KLF2, ERAS, and PRMT6 as factors enabling rabbit PSCs to generate chimeras by acquiring naive pluripotency and specific transcriptomic features.

This study identifies novel regulators of human naive pluripotency using a genetic switch that activates STAT3 and JAK signaling, revealing key genes and mechanisms involved in reprogramming.