BiochemistrybioRxivPreprint
CDC7 and CDK8 kinases cooperate to support DNA replication origin firing in human cells
Michael D. Rainey, Stefanus Bernard, Aikaterini Pravi…·Corrado Santocanale
The paper identifies CDK8 as a third kinase involved in DNA replication origin activation by showing its cooperation with CDC7 and its role in phosphorylating MCM4.
DOI 10.64898/2025.12.09.692982