Hypothalamic MCH neurons links tau pathology to sleep disruption
Ke Pang, Siyin Guo, Ruilin Yang, Ajay Kumar, Wyatt D. Morse, Leann Xu, Qiaoling Liu, Dequan Jiang, Peng Zhong
This study identifies MCH neurons in the hypothalamus as a key circuit linking tau pathology to sleep disruption and shows their potential as a therapeutic target.
bioRxiv · Jun 3, 2026 · PreprintNeuroscience