Integrin α11 is enriched in quiescence and promotes cell-cycle re-entry through destabilisation of the CDK inhibitor p27
Ekjot Kaur, Jordan A. Holt, Rona Wilson, Van Kelly, Elena Gomez Marin, Bojan Žunar, Alasdair Daniels, Rozita Adib, Philipp Thomas, Boris Lenhard, Tony Ly, Alexis R. Barr
The paper identifies integrin α11 as a quiescence signature protein that promotes cell-cycle re-entry by destabilizing the CDK inhibitor p27 through YAP-dependent regulation.
bioRxiv · Aug 31, 2026 · PreprintCell Biology