Critical role of Gα12 and Gα13 proteins in TGF-β-induced myofibroblast differentiation.
Eleanor B. Reed, Albert S. Sitikov, Kun Woo D Shin, Robert B. Hamanaka, Rengül Çetin-Atalay, Gökhan M. Mutlu, Alexander A. Mongin, Nickolai O. Dulin
This study shows that Gα12 and Gα13 proteins are essential for TGF-β-induced myofibroblast differentiation by regulating Smad phosphorylation and receptor expression.
Biochemical Journal · Dec 2, 2024Peer-reviewedCell Biology