Author

Aldo H. Corchado

Jewish General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hamed Shateri NajafabadiiD· 3 shared Darren M. BlackburniD· 2 shared Felicia Lazure· 2 shared Theodore J. PerkinsiD· 2 shared Vahab D. SoleimaniiD· 2 shared Ahmad SharanekiD· 1 shared Arezu Jahani‐AsliD· 1 shared Berat DoğaniD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenetics

Hamed Shateri NajafabadiORCID

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Author profile →

3 papers

Recent·Most cited

Myf6/MRF4 is a Myogenic Niche Regulator Required for the Maintenance of the Muscle Stem Cell Pool

Felicia Lazure, Darren M. Blackburn, Nabila Karam, Korin Sahinyan, Ahmad Sharanek, Duy Nguyen, Aldo H. Corchado, Christoph Lepper, Hamed Shateri Najafabadi, Theodore J. Perkins, Arezu Jahani‐Asl, Vahab D. Soleimani

This study shows that Myf6/MRF4 regulates myokine production and maintains the muscle stem cell pool by controlling signaling pathways like EGFR and STAT3.

EMBO Reports · Oct 13, 2020Peer-reviewedGenetics

A domain-resolution map of in vivo DNA binding reveals the regulatory consequences of somatic mutations in zinc finger transcription factors

Berat Doğan, Senthilkumar Kailasam, Aldo H. Corchado, Naghmeh Nikpoor, Hamed Shateri Najafabadi

The paper identifies DNA-binding zinc finger domains in 209 human multi-ZF proteins and shows their mutations affect gene expression in cancer.

bioRxiv · Jun 16, 2020 · PreprintBioinformatics

High Resolution Genome Wide Expression Analysis of Single Myofibers Using SMART-Seq

Darren M. Blackburn, Felicia Lazure, Aldo H. Corchado, Theodore J. Perkins, Hamed Shateri Najafabadi, Vahab D. Soleimani

This paper develops smfRNA-Seq to analyze the whole transcriptome of individual myofibers and finds aging causes significant changes in metabolic and structural gene expression.

Journal of Biological Chemistry · Nov 21, 2019Peer-reviewedMolecular Biology