Selection and structural characterisation of anti-TREM2 scFvs that reduce levels of shed ectodomain
Aleksandra Szykowska, Yu Chen, Thomas B. Smith, Charlotta Preger, Jingjing Yang, Dongming Qian, Shubhashish M. M. Mukhopadhyay, Edvard Wigren, Stephen J. Neame, S. Gräslund, Helena Persson, Peter J. Atkinson, Elena Di Daniel, Emma Mead, John C. K. Wang, , Alex N. Bullock
The paper identifies and characterizes anti-TREM2 scFv antibodies that inhibit soluble TREM2 production.
Structure · Jul 6, 2021Peer-reviewedMolecular Biology