Deep Brain Stimulation rescues the homeostasis disruption of circulating D- and L-amino acids level in men with Parkinson's Disease
Tommaso Nuzzo, Federica Carrillo, Marcello Serra, Claudia Gentile, Anna Di Maio, Alessandra Pizzella, Sara Pietracupa, Nicola Modugno, Francesco Errico, Teresa Esposito, Alessandro Usiello
This study shows that Deep Brain Stimulation (STN-DBS) restores circulating D- and L-amino acid levels in male Parkinson's patients, unlike L-DOPA therapy, and suggests these amino acids as potential early biomarkers.
Neurobiology of Disease · Oct 20, 2025Peer-reviewedNeuroscience