Alessandro L V Coradini

Synthetic collinearization of a chromosome segment enables genetic dissection of incompatibility between distant genera

This paper demonstrates that collinearization can overcome genetic incompatibility between distant yeast species by creating synthetic chromosome segments that substitute for native ones, revealing hundreds of genetic incompatibilities.

Multiple layers of cryptic genetic variation underlie a yeast complex trait

The paper identifies 21 loci underlying a yeast colony phenotype, showing cryptic genetic variation is revealed by specific perturbations and environmental contexts.