Rab12 is a regulator of mitophagy and mitochondrial homeostasis
Tara Richbourg, Alex George, Anas Bitar, Ian T. Ryde, Casey Farrell, Tuyana B. Malankhanova, Jennifer Liu, Silas A. Buck, Ivana Barraza, So Young A Kim, Xiaoyan Nie, Andrew B. West, Joel N. Meyer, Laurie H. Sanders
This study identifies Rab12 as a negative regulator of mitophagy and mitochondrial homeostasis, showing its loss increases mitochondrial clearance and sensitivity to stress.
bioRxiv · Mar 31, 2026 · PreprintCell Biology