Author

Alex Hewitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alice Pebay· 2 shared Maciej DaniszewskiiD· 2 shared Alexandra Sexton-Oates· 1 shared Alison Conquest· 1 shared Amy Fan Li· 1 shared Anna E King· 1 shared Bang V Bui· 1 shared Camden Lo· 1 shared

Activity by Year

2014-2016 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioengineering

Alice Pebay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of a modular automated system for maintenance and differentiation of adherent human pluripotent stem cells.

Duncan E Crombie, Maciej Daniszewski, Helena H Liang, Tejal Kulkarni, Fan Li, Grace E Lidgerwood, Alison Conquest, Damian Hernandez, Sandy S Hung, Katherine P Gill, Elisabeth De Smit, Lisa S Kearns, Linda Clarke, Valentin M Sluch, Xitiz Chamling, , Alice Pebay

This paper develops an automated system for maintaining and differentiating human pluripotent stem cells, enabling large-scale culture and reducing variability.

bioRxiv · Oct 5, 2016Bioengineering

DNA methylation landscape of ocular tissue relative to matched to peripheral blood.

Alex Hewitt, Vania Januar, Alexandra Sexton-Oates, Jihoon E Joo, Maria Franchina, Jie Jin Wang, Helena Liang, Jamie E Craig, Richard Saffery

The paper compares DNA methylation profiles between ocular tissues and matched peripheral blood samples, finding strong intra-individual correlations but limited covariation between blood and specific ocular tissues.

bioRxiv · Sep 14, 2016Genomics

AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo.

Sandy SC Hung, Vicki Chrysostomou, Amy Fan Li, Jeremiah KH Lim, Jiang-Hui Wang, Joseph E Powell, Leilei Tu, Maciej Daniszewski, Camden Lo, Raymond C Wong, Jonathan G Crowston, Alice Pebay, Anna E King, Bang V Bui, Guei-Sheung Liu, Alex Hewitt

This study uses AAV2 to deliver CRISPR/Cas components to retinal cells in Thy1-YFP mice, achieving an 84% reduction in YFP-positive cells without affecting retinal function.

Investigative Opthalmology & Visual Science · Jun 29, 2016Peer-reviewedGenomics

Benchmarking undedicated cloud computing providers for analysis of genomic datasets.

Seyhan Yazar, George EC Gooden, David A Mackey, Alex Hewitt

This study benchmarks two cloud computing services for genomic data analysis, finding Google Compute Engine more efficient and cost-effective than Amazon Web Services.

bioRxiv · Aug 7, 2014Bioinformatics