Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties
Héléna Boutzen, Alex Murison, Alexa Oriecuia, Suraj Bansal, Christopher Arlidge, Jean C. Y. Wang, Mathieu Lupien, Kerstin B. Kaufmann, John Edgar Dick
The paper identifies two distinct leukemia stem cell subtypes with unique transcriptional, epigenetic, and functional properties using a patient-derived cell model and single-cell analysis.
Leukemia · Aug 21, 2024Peer-reviewedCancer Biology