Author

Kerstin B. Kaufmann

University Health NetworkORCID 0000-0001-5013-6123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Angelica VaresiiD· 2 shared Héléna BoutzeniD· 2 shared John Edgar DickiD· 2 shared Liqing JiniD· 2 shared Alex Murison· 1 shared Alexa Oriecuia· 1 shared Amanda MitchelliD· 1 shared Amit SubediiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Angelica VaresiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 26, 2026

Cell-state-dependent responses to PLK1 inhibition reveal a non-canonical microtubule-endolysosomal vulnerability in quiescent leukemia stem cells

Qiang Liu, Milena Gojsevic, Angelica Varesi…·Jean CY Wang

This study shows that PLK1 inhibition eradicates quiescent leukemia stem cells through a non-canonical mechanism involving microtubule and endolysosomal disruption, distinct from its canonical mitotic function.

DOI 10.64898/2026.08.25.746864

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintAug 5, 2026

Locus-specific transposable element expression drives human hematopoietic stem cell disease pathophysiology

Angelica Varesi, Sontago Dong, Chiara Gaddoni…·John E. Dick

This study identifies locus-specific transposable elements driving VEXAS syndrome pathophysiology by regulating myeloid commitment in UBA1-mutant hematopoietic stem cells.

DOI 10.64898/2026.07.31.742092

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyLeukemiaPeer-reviewedAug 21, 2024

Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties

Héléna Boutzen, Alex Murison, Alexa Oriecuia…·John Edgar Dick

The paper identifies two distinct leukemia stem cell subtypes with unique transcriptional, epigenetic, and functional properties using a patient-derived cell model and single-cell analysis.

26 citationstop 2%

humanscRNA-seq

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