Author
University Health NetworkORCID 0000-0001-7543-3917Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Stephen E. Kurtz, Christopher A. Eide, Andy J. Kaempf…·Jeffrey W Tyner
This paper develops a rapid qPCR-based gene expression profiler to predict AML patient response to standard therapies using cell state and BCL2 family gene expression signatures.
Joana L. Araújo, Elvin Wagenblast, Véronique Voisin…·John Edgar Dick
This study shows FLT3 is essential for ITD-mutated leukemic stem cells but not for normal hematopoietic stem cells, supporting targeted therapies for AML.
Boyang Zhang, Alexander J. Murison, Angelica Varesi…·Stanley W.K. Ng
This study identifies distinct gene regulatory networks in hematopoietic stem cells and leukemia stem cells using integrated gene expression and chromatin accessibility data from AML patients and human umbilical cord blood.
Héléna Boutzen, Alex Murison, Alexa Oriecuia…·John Edgar Dick
The paper identifies two distinct leukemia stem cell subtypes with unique transcriptional, epigenetic, and functional properties using a patient-derived cell model and single-cell analysis.