Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection
Qi Guo, Keval Parikh, Jian Zhang, Alexander Brinkley, Grace L. Chen, Natnicha Jakramonpreeya, Anjie Zhen, Dong Sung An
This paper develops an HSPC-based gene therapy with anti-HIV-1 genes and a safety kill switch, showing significant viral load reduction in huBLT mice.
Molecular Therapy — Methods & Clinical Development · May 15, 2025Peer-reviewedMicrobiology