Optimizing single-cell RNA sequencing methods for human colon biopsies: droplet-based vs. picowell-based platforms
Jonathan M. Downie, Ryan J. Musich, Connor M. Geraghty, Alexander Caraballo, Shijie He, Saleh Khawaled, Kylor H. Lachut, Timothy L. Long, Julie Y. Zhou, Ömer H. Yilmaz, Thaddeus S. Stappenbeck, Andrew Tan Chan, David A. Drew
This study compares droplet-based and picowell-based single-cell RNA sequencing platforms for human colon biopsies, finding differences in cell recovery, typeability, and gene expression consistency.
bioRxiv · Jun 24, 2024 · PreprintGenomics