Author

Julie Y. Zhou

Cleveland ClinicORCID 0000-0002-1533-5183Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ömer H. YilmaziD· 2 shared Thaddeus S. StappenbeckiD· 2 shared Alexander Caraballo· 1 shared Andrei I. IvanoviD· 1 shared Andrew Tan ChaniD· 1 shared Connor M. Geraghty· 1 shared Daniel J. SilveriD· 1 shared David A. DrewiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Ömer H. YilmazORCID

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2 papers

Recent·Most cited

Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis

Julie Y. Zhou, Qiuhe Lu, Yujia Hu, Satoru Fujii, Scott T. Espenschied, Morgan J. Engelhart, Kelsey J. Lewis, Paul E. Karell, Yi Han, Heaji Shin, Robert E. Schmidt, Daniel J. Silver, Andrei I. Ivanov, Ömer H. Yilmaz, Thaddeus S. Stappenbeck

This study shows that intestinal stem cells (ISCs) enhance local mucosal immunity by engulfing apoptotic bodies, which leads to increased T cell activity through TNF signaling.

bioRxiv · Oct 29, 2024 · PreprintCell Biology

Optimizing single-cell RNA sequencing methods for human colon biopsies: droplet-based vs. picowell-based platforms

Jonathan M. Downie, Ryan J. Musich, Connor M. Geraghty, Alexander Caraballo, Shijie He, Saleh Khawaled, Kylor H. Lachut, Timothy L. Long, Julie Y. Zhou, Ömer H. Yilmaz, Thaddeus S. Stappenbeck, Andrew Tan Chan, David A. Drew

This study compares droplet-based and picowell-based single-cell RNA sequencing platforms for human colon biopsies, finding differences in cell recovery, typeability, and gene expression consistency.

bioRxiv · Jun 24, 2024 · PreprintGenomics