Increased susceptibility to intracellular bacteria and necrotic inflammation driven by a dysregulated macrophage response to TNF
Bidisha Bhattacharya, Sujoy Chattrerjee, Robert Berland, Alexander Pichugin, Yuanwei Gao, John Connor, Alexander Ivanov, Bo-Shiun Yan, Lester Kobzik, Igor Kramnik
The paper identifies a dysregulated macrophage response to TNF in sst1-deficient mice, leading to increased susceptibility to intracellular bacteria and necrotic inflammation.
bioRxiv · Mar 15, 2018 · PreprintImmunology