Author

Alexander Luchak

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bana SammaniD· 1 shared Boyan K. TsankoviD· 1 shared Charles CarriD· 1 shared Dana J. PhilpottiD· 1 shared Derek K.L. TsangiD· 1 shared Elaine Tam· 1 shared Giuliano BayeriD· 1 shared Jennifer L. GommermaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Bana SammanORCID

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1 paper

Recent·Most cited

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Boyan K. Tsankov, Madison Denney, Jennifer S. Y. Ahn, Charles Carr, Nayanan Nathan, Derek K.L. Tsang, Giuliano Bayer, Lauren Baerg, Alexander Luchak, Tapas Mukherjee, Elaine Tam, Bana Samman, Jennifer L. Gommerman, Stephen E. Girardin, Dana J. Philpott

This study shows that NOD2 signaling in endothelial cells regulates intestinal immune responses by promoting T cell homing and memory formation, and its loss contributes to Crohn's disease inflammation.

Nature Immunology · Jul 20, 2026Peer-reviewedImmunology