Polycomb Repressive Complex 2 is critical for mouse cortical glutamatergic neuron development
Laura Currey, Benjamin Mitchell, Majd Al‐Khalily, Sarah-Jayne McElnea, Peter Kozulin, Danyon Harkins, Alexandra Pelenyi, Laura R. Fenlon, Rodrigo Suárez, Nyoman Dana Kurniawan, Thomas H.J. Burne, Lachlan Harris, Stefan Thor, Michael Piper
This study investigates the role of PRC2 in mouse cortical development, finding that homozygous mutations lead to structural and neuronal dysregulation, while heterozygous mutations show distinct effects.
Cerebral Cortex · Jun 16, 2024Peer-reviewedDevelopmental Biology