Stefan Thor

This study characterizes the cellular and morphogenetic events of sponge metamorphosis, revealing a coordinated program involving epithelial infoldings and cell transitions.

This paper identifies Vgll2 and Tead1 as key regulators of Hcrt neuron generation in mouse and human, showing their role in differentiation and potential for cell therapy.

This study investigates the role of PRC2 in mouse cortical development, finding that homozygous mutations lead to structural and neuronal dysregulation, while heterozygous mutations show distinct effects.

Cytocipher identifies significant cell populations in scRNA-seq data by statistically determining transcriptionally distinct clusters, revealing new cell types and subpopulations across various biological contexts.

This study shows that while most hypothalamic neurons develop normally without the H3K27me3 epigenetic mark, specific neuronal subtypes are sensitive to its loss.

The paper investigates the role of PRC2 in mouse CNS development by integrating transcriptomic and epigenetic data to reveal layered regulatory mechanisms.

The paper identifies SoxB and Snail genes as additional proneural factors interacting with Notch and EMT genes to regulate neuroblast selection in Drosophila.