Astrocytic GABA transport controls fidelity of temporal processing
Victoria A. Wagner, Ritika Thapa, Anna O. Norman, Alexandra Varallo, Jordan Wimberly, Maham Rais, Dmytro Gerasymchuk, Petteri T. Piepponen, Khaleel A. Razak, Maija L. Castrén, Iryna M. Ethell
This study shows that impaired astrocytic GABA transport in Fragile X syndrome contributes to hyperexcitability and behavioral abnormalities, and blocking this transport can restore normal function.
bioRxiv · Feb 8, 2022 · PreprintNeuroscience