Author

Maija L. Castrén

University of California, RiversideORCID 0000-0002-9644-5295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra Varallo· 1 shared Ana R. Colaço· 1 shared Anna O. Norman· 1 shared Bernice SimiD· 1 shared Carola I. RadulescuiD· 1 shared Dmytro Gerasymchuk· 1 shared Georgia ChaldaiopoulouiD· 1 shared Han‐Gyu BaeiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alexandra Varallo

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Astrocytic GABA transport controls fidelity of temporal processing

Victoria A. Wagner, Ritika Thapa, Anna O. Norman, Alexandra Varallo, Jordan Wimberly, Maham Rais, Dmytro Gerasymchuk, Petteri T. Piepponen, Khaleel A. Razak, Maija L. Castrén, Iryna M. Ethell

This study shows that impaired astrocytic GABA transport in Fragile X syndrome contributes to hyperexcitability and behavioral abnormalities, and blocking this transport can restore normal function.

bioRxiv · Feb 8, 2022 · PreprintNeuroscience

Integrative analysis identifies key molecular signatures underlying neurodevelopmental deficits in Fragile X Syndrome

Kagistia Hana Utami, Niels Henning Skotte, Ana R. Colaço, Nur Amirah Binte Mohammad Yusof, Bernice Sim, Xin Yi Yeo, Han‐Gyu Bae, Marta Garcia‐Miralles, Carola I. Radulescu, Qiyu Chen, Georgia Chaldaiopoulou, Herty Liany, Srikanth Nama, Ulla‐Kaisa Peteri, Prabha Sampath, , Mahmoud A. Pouladi

The paper identifies molecular signatures and neurodevelopmental abnormalities in FMRP-deficient neurons derived from isogenic FMR1 knockout human embryonic stem cells.

Biological Psychiatry · May 13, 2020Peer-reviewedNeuroscience