Auranofin shows bactericidal activity in Pseudomonas aeruginosa by targeting thiol homeostasis
Alexandre Lüscher, Yves Mattenberger, Léna Falconnet, Natacha Civic, Christian van Delden, Thilo Köhler
This study identifies auranofin as a bactericidal agent against Pseudomonas aeruginosa by targeting thiol homeostasis, highlighting the value of overcoming efflux barriers to discover new antibiotics.
bioRxiv · Sep 12, 2026 · PreprintMicrobiology