Author

Christian van Delden

University of GenevaORCID 0000-0002-2901-8285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Organism:human· 1

Frequent Co-Authors

Alexandre Lüscher· 2 shared Léna Falconnet· 2 shared Thilo KöhleriD· 2 shared Angela KoutsokeraiD· 1 shared Gilbert GreubiD· 1 shared Grégory BerraiD· 1 shared Marc ChansoniD· 1 shared Marie Graindorge BeaumeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Alexandre Lüscher

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Auranofin shows bactericidal activity in Pseudomonas aeruginosa by targeting thiol homeostasis

Alexandre Lüscher, Yves Mattenberger, Léna Falconnet, Natacha Civic, Christian van Delden, Thilo Köhler

This study identifies auranofin as a bactericidal agent against Pseudomonas aeruginosa by targeting thiol homeostasis, highlighting the value of overcoming efflux barriers to discover new antibiotics.

bioRxiv · Sep 12, 2026 · PreprintMicrobiology

Adaptation of Pseudomonas aeruginosa to the lung allograft environment in cystic fibrosis lung transplant recipients

Thilo Köhler, Léna Falconnet, Alexandre Lüscher, Marie Graindorge Beaume, Marc Chanson, Gilbert Greub, Angela Koutsokera, Grégory Berra, Paola M. Soccal, Christian van Delden, the Swiss Transplant Cohort Study

This study investigates how Pseudomonas aeruginosa adapts to the non-CF lung allograft environment in cystic fibrosis transplant recipients, finding mutations linked to lifestyle changes and persistence from sinus seeding.

bioRxiv · Jul 6, 2026 · PreprintMicrobiology