Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment
Raphael O. Betschart, Alexandre Thiéry, Domingo Aguilera‐Garcia, Martin Zoche, Holger Moch, Raphael Twerenbold, Tanja Zeller, Stefan Blankenberg, Andreas Ziegler
This study compares WGS pipelines, finding DRAGEN outperforms GATK in speed and accuracy for variant calling and mapping.
Scientific Reports · Dec 13, 2022Peer-reviewedBioinformatics