Author

Alexis G. Sommerfield

New York University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrew J. DarwiniD· 2 shared Julia MamanaiD· 1 shared Michelle WangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

Andrew J. DarwinORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 12, 2026

LytM family endopeptidase LmdC is controlled by regulated auto processing and proteolytic destruction in Pseudomonas aeruginosa

Alexis G. Sommerfield, Andrew J. Darwin

This study identifies a novel regulatory mechanism for the LytM/M23 family endopeptidase LmdC in P. aeruginosa, showing it is auto-cleaved and degraded by proteases Prc and CtpA, with inhibition by Baf and Api.

DOI 10.64898/2026.10.09.758143

bacteria (other)experimental assay

𝕏 PostBluesky

MicrobiologyJournal of BacteriologyPeer-reviewedSep 17, 2024

In vivo and in vitro analysis of the role of the Prc protease in inducing mucoidy in Pseudomonas aeruginosa

Alexis G. Sommerfield, Michelle Wang, Julia Mamana, Andrew J. Darwin

This paper clarifies the role of Prc protease in mucoid conversion of Pseudomonas aeruginosa by showing it directly degrades MucA22, a truncated form of MucA, and not wild-type MucA.

3 citations

bacteria (other)experimental assay

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