Mammalian RAD51 prevents non-conservative alternative end-joining and single strand annealing through non-catalytic mechanismssms
Ayeong So, Ali Akbar Muhammad, Catherine Chailleux, Laura Sesma-Sanz, Sandrine Ragu, Éric Le Cam, Yvan Canitrot, Jean‐Yves Masson, Dupaigne Pauline, Bernard S. López, Josée Guirouilh‐Barbat
This study shows RAD51 inhibits non-conservative DNA repair pathways by blocking ssDNA annealing, independent of its catalytic activity.
bioRxiv · Sep 23, 2019 · PreprintMolecular Biology