Author

Josée Guirouilh‐Barbat

Centre National de la Recherche ScientifiqueORCID 0000-0002-8845-7333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ayeong So· 2 shared Bernard S. LópeziD· 2 shared Ali Akbar Muhammad· 1 shared Catherine ChailleuxiD· 1 shared Chloé LescaleiD· 1 shared Dupaigne PaulineiD· 1 shared Elisa Yaniz‐GalendeiD· 1 shared Éric Le CamiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Ayeong So

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 23, 2019

Mammalian RAD51 prevents non-conservative alternative end-joining and single strand annealing through non-catalytic mechanismssms

Ayeong So, Ali Akbar Muhammad, Catherine Chailleux…·Josée Guirouilh‐Barbat

This study shows RAD51 inhibits non-conservative DNA repair pathways by blocking ssDNA annealing, independent of its catalytic activity.

6 citations

experimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintSep 14, 2019

RAD51 promotes non-homologous genetic rearrangements that are prevented by 53BP1

Josée Guirouilh‐Barbat, Wei Yu, Loélia Babin…·Bernard S. López

The paper shows RAD51 and BRCA2 promote non-homologous genetic rearrangements, which are prevented by 53BP1, and links BRCA2 proficiency to increased non-homologous sequence capture in breast tumors.

1 citation

humanstatistical model

𝕏 PostBluesky