Cocaine withdrawal enhances subthalamic reward sensitivity
Maya Williams, Cassandre Vielle, Jeanne-Laure de Peretti, Alix Tiran‐Cappello, Christophe Melon, Ali Awada, Yann Pelloux, Nicolas Maurice, Christelle Baunez, Mickaël Degoulet
This study shows that cocaine withdrawal increases reward sensitivity in the subthalamic nucleus, suggesting a potential mechanism for the therapeutic effects of deep brain stimulation in addiction.
bioRxiv · Jun 10, 2025 · PreprintNeuroscience