Christelle Baunez

Subthalamic Nucleus Optogenetic Inhibition Bidirectionally Regulates Social Motivation According to Familiarity and Social Hierarchy

This study investigates how familiarity and social hierarchy influence social motivation in male and female rats, showing the subthalamic nucleus (STN) plays a role in regulating these behaviors.

THE SUBTHALAMIC NUCLEUS IS INVOLVED IN SOCIAL MEMORY IN MALE RATS

This study investigates the role of the subthalamic nucleus in social memory in male rats using pharmacological, optogenetic, and electrical stimulation methods, finding that STN manipulations selectively impair social discrimination memory.

Presence of an unfamiliar peer reverses escalated cocaine intake in male rats: involvement of the subthalamic nucleus

This study shows that the presence of an unfamiliar peer reduces cocaine intake in male rats, with the subthalamic nucleus mediating this effect during both short and long-access sessions.

Cocaine withdrawal enhances subthalamic reward sensitivity

This study shows that cocaine withdrawal increases reward sensitivity in the subthalamic nucleus, suggesting a potential mechanism for the therapeutic effects of deep brain stimulation in addiction.

Cocaine extended access gates compulsive-like seeking in rats

This study introduces a new behavioral task to assess compulsive-like cocaine seeking in rats and shows it emerges after extended access with punishment.

SUBTHALAMIC HIGH-FREQUENCY DEEP BRAIN STIMULATION REDUCES ADDICTION-LIKE ALCOHOL USE AND SUPPRESSES THE OVERCONSUMPTION INDUCED BY THE PEER S PRESENCE

This study examines how peer presence affects alcohol consumption in rats and evaluates the impact of subthalamic nucleus deep brain stimulation on this behavior.

Social Context and Drug Cues Modulate Inhibitory Control in Cocaine Addiction: involvement of the STN evidenced through Functional Magnetic Resonance Imaging

This study shows that social context and drug cues affect inhibitory control in cocaine use disorder, with the subthalamic nucleus involved, using fMRI.

THE SUBTHALAMIC NUCLEUS IS INVOLVED IN SOCIAL RECOGNITION MEMORY IN RATS

This study investigates the role of the subthalamic nucleus in social recognition memory in rats using lesions and optogenetic manipulations, finding that STN activity is necessary for proper social recognition memory.

Peer presence and familiarity as key factors to reduce cocaine intake: an effect mediated by the Subthalamic Nucleus

This study shows that peer presence and unfamiliarity reduce cocaine intake in rats and humans, with the subthalamic nucleus mediating this effect.

Low frequency oscillatory activity of the subthalamic nucleus is a predictive biomarker of compulsive-like cocaine seeking.

The paper identifies low frequency STN oscillations as a biomarker predicting compulsive-like cocaine seeking in rodents and shows DBS can modulate this behavior.

Subthalamic nucleus mediates the modulation on cocaine self-administration induced by ultrasonic vocalizations playback in rats

The paper investigates how ultrasonic vocalizations (USV) affect cocaine self-administration in rats and shows that subthalamic nucleus (STN) lesions block this effect.

A glimpse at deep brain stimulation mechanisms using subthalamic nucleus optogenetic manipulations

This study uses optogenetic manipulations in rats to investigate how subthalamic nucleus activity affects motivation for food and cocaine, revealing differences between optogenetic and electric deep brain stimulation effects.

Peer presence and familiarity as key factors to reduce cocaine intake: evidence from translational research

This study shows that peer presence and unfamiliarity reduce cocaine and stimulant intake in both rats and humans.