Systems BiologybioRxivPreprint
Characterising AlphaFold 3s ability to predict T cell antigen specificity
Benjamin McMaster, Ali El Moselhy, Ilija Ilievski…·Hashem Koohy
This study evaluates AlphaFold 3's ability to predict T cell antigen specificity using structural models and finds that binding scores correlate with TCR positioning over pMHC, not chemical interactions.
2 citations