Author
Institut universitaire de cardiologie et de pneumologie de Québec
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Yann Grobs, Sarah-Eve S Lemay, Manon Mougin…·Sébastien Bonnet
This study identifies hypusine signaling as a driver of vascular smooth muscle cell proliferation in restenosis and shows that inhibiting DHPS reduces neointimal hyperplasia in preclinical models and human tissue.
Rafael Sobrano Fais, Erica Das Neves Palotta, Katrina W. Kopf…·Tim Lahm
This study identifies a sexually dimorphic NLRP3 signaling pathway in right ventricular failure, showing estrogen receptor α mediates protection against NLRP3-induced contractile dysfunction in cardiomyocytes.
Sarah-Eve S Lemay, Mónica S. Montesinos, Yann Grobs…·Sébastien Bonnet
The study identifies integrin α5β1 as a key driver of pulmonary vascular remodeling in PAH and shows its inhibition improves hemodynamics and RV function in preclinical models.
Yann Grobs, Charlotte Romanet, Sarah-Eve Lemay…·Sebastien Bonnet
This study identifies ATP-citrate lyase as a driver of vascular remodeling in pulmonary hypertension and coronary artery disease, showing its inhibition can reverse pathological changes.