Immunostimulatory guide RNAs mediate potent antiviral response
Yujia Cai, Alice Knudsen, Samuel Joseph Windross, Martin K Thomsen, Søren R Paludan
This study shows that IVT-gRNA induces strong cytokine expression and antiviral activity against HSV-1 through immune stimulation, enhancing CRISPR's therapeutic potential.
bioRxiv · Mar 15, 2018 · PreprintImmunology