Bridging Gaps in Antibody Responses and Animal Welfare: Assessing Blood Collection Methods and Vaginal Immunity in Mice Immunized with Intranasal Gonococcal Vaccines
Abhishek Chanda, Yujuan Song, Junaid Nazir, Chenwei Lin, Alicia Cheng, Jennifer Sargent, Aleksandra E. Sikora
This study compares retro-orbital and saphenous vein blood collection methods in mice immunized with intranasal gonococcal vaccines, finding SV sampling may better assess functional antibody responses and improve animal welfare.
bioRxiv · Feb 23, 2025 · PreprintMicrobiology