Author

Aleksandra E. Sikora

Oregon State UniversityORCID 0000-0001-7977-2596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Abhishek Chanda· 3 shared Junaid NaziriD· 2 shared Alicia Cheng· 1 shared Alison K. CrissiD· 1 shared Andreea WaltmanniD· 1 shared Andrew N Macintyre· 1 shared Andrew N. MacintyreiD· 1 shared Ann E. JerseiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

Abhishek Chanda

Mutual co-authors in cluster

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 3, 2026

Mucosal ACP subunit vaccine formulated with a small molecule STING agonist drives protective TH1/TH17 responses and serum bactericidal antibodies against Neisseria gonorrhoeae

Abhishek Chanda, Ines A Cadena, Junaid Nazir…·Aleksandra E. Sikora

This study evaluates a mucosal vaccine combining ACP and diABZI, showing enhanced TH1/TH17 responses and serum bactericidal activity against Neisseria gonorrhoeae.

DOI 10.64898/2026.11.02.763630

humanmouse

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MicrobiologybioRxivPreprintJul 16, 2026

An mRNA-Lipid Nanoparticle Platform Encoding the Conserved Outer Membrane Protein BamA Elicits Broadly Cross-Reactive Systemic and Mucosal Antibodies Against Antimicrobial-Resistant Neisseria gonorrhoeae

Natalie Wolske, Namratha Turuvekere Vittala Murthy, Abhishek Chanda…·Aleksandra E. Sikora

This paper evaluates an mRNA-LNP vaccine encoding BamA against N. gonorrhoeae, showing it elicits cross-reactive antibodies but lacks protective efficacy in mice.

DOI 10.64898/2026.07.14.738439

mouseprotein sequence

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MicrobiologyFrontiers in ImmunologyPeer-reviewedApr 11, 2025

Protection against N. gonorrhoeae induced by OMV-based Meningococcal Vaccines are associated with cross-species directed humoral and cellular immune responses

Weiyan Zhu, Andreea Waltmann, Marguerite B. Little…·Joseph A. Duncan

This study investigates cross-species immune responses induced by meningococcal OMV vaccines and their association with protection against N. gonorrhoeae.

12 citationstop 3%

mouseproteomics

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MicrobiologybioRxivPreprintFeb 23, 2025

Bridging Gaps in Antibody Responses and Animal Welfare: Assessing Blood Collection Methods and Vaginal Immunity in Mice Immunized with Intranasal Gonococcal Vaccines

Abhishek Chanda, Yujuan Song, Junaid Nazir…·Aleksandra E. Sikora

This study compares retro-orbital and saphenous vein blood collection methods in mice immunized with intranasal gonococcal vaccines, finding SV sampling may better assess functional antibody responses and improve animal welfare.

DOI 10.1101/2025.02.23.639724

mousebulk RNA-seq

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