Metabolic Alteration in Oxylipins and Endocannabinoids Point to an Important Role for Soluble Epoxide Hydrolase and Inflammation in Alzheimer's Disease - Finding from Alzheimer's Disease Neuroimaging Initiative.
Kamil Borkowski, Chunyuan Yin, Alida Kindt, Nuanyi Liang, Elizabeth C. M. de Lange, Colette Blach, John W. I. Newman, Rima F Kaddurah-Daouk, Thomas Hankemeier, the Frontotemporal Lobar Degeneration Neuroimaging Initiative
The paper analyzes metabolites in AD patients to show inflammation and sEH dysregulation, with sex and disease stage differences, and identifies markers of disease progression and cognitive resilience.
Alzheimer s Research & Therapy · Jan 7, 2026Peer-reviewedNeuroscience