Serine metabolism changes link sphingolipid and one-carbon metabolism to cardiovascular risk factors in a cross-sectional study of asymptomatic adults
Mengjiang Huang, Debra K. Tacad, Tong Shen…·John W. I. Newman
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Agricultural Research ServiceORCID 0000-0001-9632-6571Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Mengjiang Huang, Debra K. Tacad, Tong Shen…·John W. I. Newman
Kamil Borkowski, Chunyuan Yin, Alida Kindt…·the Frontotemporal Lobar Degeneration Neuroimaging Initiative
The paper analyzes metabolites in AD patients to show inflammation and sEH dysregulation, with sex and disease stage differences, and identifies markers of disease progression and cognitive resilience.
Mike Lange, Michele Wölk, Vivian Wen Li…·James A. Olzmann
This study identifies FSP1 as a critical regulator of lipid droplet quality control, preventing neutral lipid peroxidation and ferroptosis by recycling CoQ10.
Larissa Jank, Saumitra Sen Singh, Judy J. Lee…·Pavan Bhargava
The paper shows that indole lactate (ILA), reduced in MS, restores gut microbiome metabolic balance, promoting remyelination and reducing neuroinflammation.
Brian A. Harsch, Kamil Borkowski, Rachel E. Walker…·Gregory C. Shearer
The paper investigates how ABCA1 and apoA-I facilitate 12-HETE efflux from macrophages, reducing inflammation by modulating intracellular HETE levels.