Removal of KCNQ2 from Parvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine
Junzhan Jing, Corrinne Dunbar, Alina Sonesra, Ana G. Chavez, Suhyeorn Park, Ryan Yang, Heun Soh, Maxwell Y Lee, Anastasios V. Tzingounis, Edward C. Cooper, Xiaolong Jiang, Atul Maheshwari
This study shows that removing KCNQ2 from parvalbumin-expressing interneurons enhances the anti-seizure efficacy of retigabine.
bioRxiv · Dec 9, 2020Neuroscience